Based on the trailer, it seems the premise of the film is that aliens receive a message from Earth and decide to fight back with vintage arcade characters, including ones from Space Invaders, Q*bert and Donkey Kong. To defeat these baddies, Sandler and Co must beat them in the style of their respective games.
When it comes time to take out the giant glowing-yellow Pac-Man, their plan includes outfitting a quartet of Mini Cooper S models as the ghosts. Squint at the cars' license plates to spot a subtle, visual joke. They are called Inky, Pinky, Blinky and Clyde – the nicknames of the enemies in the arcade.
While it could be argued that Sandler and James haven't quite been at the top of their games recently, the story here appears to boil down to Ghostbusters with video games, which could work purely on a nostalgic level if it's properly handled. Check out the trailer to spot even more vintage arcade references.