Thaiyotakamli Supersonic July 16, 2015 Share July 16, 2015 (edited) 有得救 http://www.channelnewsasia.com/mobile/singapore/made-in-singapore-cancer/1988090.html SINGAPORE: A made-in-Singapore cancer drug is touted to be the first publicly-funded drug candidate discovered and developed in Singapore to make it to trials on humans. In a statement on Thursday (Jul 16), The Agency for Science, Technology and Research (A*STAR) and Duke-National University of Singapore Graduate Medical School (Duke-NUS), announced the start of the Phase I clinical trial of novel cancer drug candidate, ETC-159. The Phase I clinical trial is meant to evaluate the safety and tolerability of ETC-159 in advanced solid tumours of up to 58 patients, and the first patient was dosed on Jun 18. The first two sites for the trial are the National Cancer Centre Singapore and the National University Hospital, and sites in the US will be added as the trial progresses. The drug is expected to target a range of cancers, including colorectal, ovarian and pancreatic cancers. These cancers are linked to a group of cell signalling pathways known as Wnt signalling, which have been identified to promote cancer growth and spread, said the agencies. ETC-159 acts as an inhibitor of these pathways. "This drug candidate therefore offers a promising novel and targeted cancer therapy that could shape future cancer therapeutic strategies," said A*STAR and Duke-NUS. ETC-159 was discovered and developed through a collaboration between A*STARs Experimental Therapeutics Centre (ETC), Drug Discovery and Development (D3) unit and Duke-NUS since 2009. It was based on the discovery work of Prof David Virshup from Duke-NUS. Prof David Virshup, inaugural Director of the Programme in Cancer and Stem Cell Biology at Duke-NUS, said: As the drug candidate provides a targeted cancer therapy, it could potentially minimise side effects and make cancer treatments more bearable for cancer patients." He added: "It is fitting that Singaporeans might be the first to benefit from this Singapore-developed drug." Edited July 16, 2015 by Thaiyotakamli ↡ Advertisement 1 Link to post Share on other sites More sharing options...
Toothiewabbit Supersonic July 16, 2015 Share July 16, 2015 (edited) Hope no one turned into zombies during trials. . Edited July 16, 2015 by Toothiewabbit 1 Link to post Share on other sites More sharing options...
Thaiyotakamli Supersonic July 16, 2015 Author Share July 16, 2015 Hope no one turned into zombies during trials. . Hope this drug will help to cure cancer in effortless and painless way 1 Link to post Share on other sites More sharing options...
Matrix0405 5th Gear August 13, 2015 Share August 13, 2015 Which public hospital is best for treating lung cancer? Link to post Share on other sites More sharing options...
Matrix0405 5th Gear August 14, 2015 Share August 14, 2015 These targeted drugs are good. In the past Chemo is like meeting an unscrupulous car mech - aircon not cold, just change all the parts and see if it works. Any experts here can compare John Hopkins TTSH vs NCC SGH? Link to post Share on other sites More sharing options...
Angcheek Hypersonic August 14, 2015 Share August 14, 2015 @@lala81 you a doctor ? 4 Link to post Share on other sites More sharing options...
Lala81 Hypersonic August 15, 2015 Share August 15, 2015 These targeted drugs are good. In the past Chemo is like meeting an unscrupulous car mech - aircon not cold, just change all the parts and see if it works. Any experts here can compare John Hopkins TTSH vs NCC SGH? I would go NCC or NUH. Just my personal preference. Link to post Share on other sites More sharing options...
Thaiyotakamli Supersonic August 15, 2015 Author Share August 15, 2015 Which public hospital is best for treating lung cancer? U can give changi a miss I think for public SGH would probably the best Link to post Share on other sites More sharing options...
Kb27 Supersonic August 15, 2015 Share August 15, 2015 These targeted drugs are good. In the past Chemo is like meeting an unscrupulous car mech - aircon not cold, just change all the parts and see if it works. Any experts here can compare John Hopkins TTSH vs NCC SGH? chemo is a weapon of mass destruction, like the nuclear bomb, good and bad both died. ↡ Advertisement Link to post Share on other sites More sharing options...
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