Dleodleo Twincharged April 11, 2018 Share April 11, 2018 https://www.telegraph.co.uk/news/science/science-news/11320497/Most-cancers-are-caused-by-bad-luck-not-genes-or-lifestyle-say-scientists.html Most cancers are caused by bad luck not genes or lifestyle, say scientists By Sarah Knapton, Science Editor 1 Jan 2015 Scientists at Johns Hopkins University School of Medicine in the US found that the majority of cancers are not linked to environment or lifestyle. Cancer-desktop2_3152434b.jpg The majority of cancers are the result of bad luck rather than unhealthy lifestyles or inherited genetic faults, scientists have discovered. For years health experts have warned that tumours are driven by a bad diet, lack of exercise, or gene errors passed down from parents. The government even set up its ‘100,000 Genomes Project’ to try and find the genetic causes of many rare diseases and cancers. But now a study has shown that most cancers are primarily caused by bad luck rather than poor lifestyle choices or defective DNA. Researchers found that more than two thirds of cancers are driven by random mistakes in cell division which are completely outside of our control. They found that the more cells need to divide to stay healthy, the more likely cancer is to develop. It is the first time that scientists have been able to explain why some cancers are more common than others. It explains why, for example, colon cancer is more prevalent than cancer of the small intestine, because cells in the colon divide twice as fast as those in the upper bowel. Of 31 cancers studied by scientists at Johns Hopkins University School of Medicine in the US, just nine were found to be linked to lifestyle or genetic faults. The remaining 22 were mainly just the result of ‘bad luck,’ with DNA and behaviour only having a small impact. The scientists claim that because it is impossible to prevent most types of cancer through behavioural changes or genetic screening, more should be done to speed up diagnosis so they can be spotted as early as possible. "If two-thirds of cancer incidence across tissues is explained by random DNA mutations that occur when stem cells divide, then changing our lifestyle and habits will be a huge help in preventing certain cancers, but may not be as effective for a variety of others,” said Dr Cristian Tomasetti. "We should focus more resources on finding ways to detect such cancers at early, curable stages." Cell division is important to renew the body and repair damage. But sometimes one chemical letter in DNA is incorrectly swapped for another during the replication process which drives the production of cancerous cells. Scientists looked at the number of cell divisions of 31 types of bodily tissue and compared them with the overall incidence of cancer in the population of America. They found that the more cell mutations occurred, the higher the rate of cancer, suggesting that it was the number of random errors in replication that was driving tumours rather than outside environmental forces. For example the cells of the pancreas regenerate far more quickly than those of the pelvis, which is why pancreatic cancer is far more common than pelvic cancer. However some cancers such as lung and skin cancer had higher rates than their mutations should predict, suggesting that genetics or lifestyle factors had increased the risk. Lead researcher Professor Bert Vogelstein, said: "Cancer-free longevity in people exposed to cancer-causing agents, such as tobacco, is often attributed to their 'good genes,' but the truth is that most of them simply had good luck. “Our study shows, in general, that a change in the number of stem cell divisions in a tissue type is highly correlated with a change in the incidence of cancer in that same tissue. "We found that the types of cancer that had higher risk than predicted by the number of stem cell divisions were precisely the ones you'd expect, including lung cancer, which is linked to smoking; skin cancer, linked to sun exposure; and forms of cancers associated with hereditary syndromes." However health experts said the study demonstrates how important it is to help lower the risk of certain cancers by eating healthily, exercising and giving up smoking. “While some genetic mistakes are due to bad luck, we know that our cancer risk depends on a combination of our genes, our environment and other aspects of our lives, many of which we can control,” said Dr Emma Smith, senior science information officer at Cancer Research UK. “We estimate that more than four in 10 cancers could be prevented by lifestyle changes, like not smoking, keeping a healthy weight, eating a healthy diet and cutting back on alcohol. “Making these changes is not a guarantee against cancer, but it stacks the odds in our favour. “It's vital that we continue making progress to detect cancer earlier and improve treatments.” Prof Hans Clevers, a stem cell and cancer biologist at the Hubrecht Institute in Utrecht, the Netherlands, said the research would help cancer patients to realise that the disease was not their fault. “The average cancer patient is just unlucky,” said Prof Clevers The research was published in the Journal Science. Bad luck? Then my MIL's family bad luck lor. All her 4 siblings had passed away from various Cancer - breast, cervical, lung and brain. She is the only sibling left but is also a cancer patient. She has to go to hospital for follow up every 2 weeks. I think it is more of genes? ↡ Advertisement Link to post Share on other sites More sharing options...
13177 Supersonic April 11, 2018 Share April 11, 2018 Just don't compound it. Chronic back pain, knee pain, diabetes, hpb, all are suffering that can be controlled by not being sedentary. Many chronic illness can be control and yet they might affect the quality of your life. Link to post Share on other sites More sharing options...
Ender Hypersonic April 11, 2018 Share April 11, 2018 Cancer or not, life is always better without gout, bodily pains, etc. they can be stuck with you for many years, çä¸å¦æ». Drink this one three times a day, can or not ? This one effective for lau sai. Got carbon. LOL 1 Link to post Share on other sites More sharing options...
Carbon82 Moderator April 11, 2018 Share April 11, 2018 https://www.telegraph.co.uk/news/science/science-news/11320497/Most-cancers-are-caused-by-bad-luck-not-genes-or-lifestyle-say-scientists.html Most cancers are caused by bad luck not genes or lifestyle, say scientists By Sarah Knapton, Science Editor 1 Jan 2015 Scientists at Johns Hopkins University School of Medicine in the US found that the majority of cancers are not linked to environment or lifestyle. Cancer-desktop2_3152434b.jpg The majority of cancers are the result of bad luck rather than unhealthy lifestyles or inherited genetic faults, scientists have discovered. For years health experts have warned that tumours are driven by a bad diet, lack of exercise, or gene errors passed down from parents. The government even set up its ‘100,000 Genomes Project’ to try and find the genetic causes of many rare diseases and cancers. But now a study has shown that most cancers are primarily caused by bad luck rather than poor lifestyle choices or defective DNA. So Bad Luck not only causes MRT to breakdown, but also cancers? Ehmmm interesting... Anyway, in the recent years, after coming across so many unfortunate events (with friends and relatives), I have learned that A positive attitude and open mind towards life will make us happier, and live longer, I believe... 7 Link to post Share on other sites More sharing options...
Weez911 Supersonic April 11, 2018 Share April 11, 2018 Bad luck? Then my MIL's family bad luck lor. All her 4 siblings had passed away from various Cancer - breast, cervical, lung and brain. She is the only sibling left but is also a cancer patient. She has to go to hospital for follow up every 2 weeks. I think it is more of genes? According to this publication, 2/3 of cancers are due to bad luck, 1/3 are due to lifestyle and genes. There are 100+ cancers by the way. 2 Link to post Share on other sites More sharing options...
inlinesix Supersonic April 11, 2018 Share April 11, 2018 On Sunday, in the midst of racing, 23 y/o young pro cyclist died from heart attack. Pro athletes go through all kind of health check also cannot escape. Treasure life Piak piak FTW 3 Link to post Share on other sites More sharing options...
Jman888 Moderator April 11, 2018 Share April 11, 2018 On Sunday, in the midst of racing, 23 y/o young pro cyclist died from heart attack. Pro athletes go through all kind of health check also cannot escape. Treasure life Piak piak FTW piak piak marathon sounds more healthy 4 Link to post Share on other sites More sharing options...
13177 Supersonic April 11, 2018 Share April 11, 2018 On Sunday, in the midst of racing, 23 y/o young pro cyclist died from heart attack. Pro athletes go through all kind of health check also cannot escape. Treasure life Piak piak FTW If you are in bad luck, anyone also cannot escape, no matter how healthy, fit and strong you are. If you are in good luck, even you smoke, drink and eat unhealthy also nothing will happen. Link to post Share on other sites More sharing options...
inlinesix Supersonic April 11, 2018 Share April 11, 2018 If you are in bad luck, anyone also cannot escape, no matter how healthy, fit and strong you are. If you are in good luck, even you smoke, drink and eat unhealthy also nothing will happen. That's whyPiak Piak FTW Link to post Share on other sites More sharing options...
Ender Hypersonic April 11, 2018 Share April 11, 2018 If you are in bad luck, anyone also cannot escape, no matter how healthy, fit and strong you are. If you are in good luck, even you smoke, drink and eat unhealthy also nothing will happen. In statisticsl term, these are outliers. Not many from the group of healthy/fit vs unhealthy. Usually don't count them in for consideration. Link to post Share on other sites More sharing options...
13177 Supersonic April 11, 2018 Share April 11, 2018 In statisticsl term, these are outliers. Not many from the group of healthy/fit vs unhealthy. Usually don't count them in for consideration. Like this how then? Lol. Link to post Share on other sites More sharing options...
Mustank Hypersonic April 11, 2018 Share April 11, 2018 For piak piak!!!!!!! 3 Link to post Share on other sites More sharing options...
Ender Hypersonic April 11, 2018 Share April 11, 2018 (edited) Like this how then? Lol.Just assume you are not the outliers(since they are rare) and do your best to be in the statistically lower risk group. Edited April 11, 2018 by Ender Link to post Share on other sites More sharing options...
Celicar Turbocharged April 11, 2018 Share April 11, 2018 piak piak marathon sounds more healthy If you are unlucky and you do this, you get free mushrooms and flowers of varying degrees of colour and itchiness. 1 Link to post Share on other sites More sharing options...
DACH Supersonic April 11, 2018 Share April 11, 2018 piak piak marathon sounds more healthy Then won't die of cancer but die of AIDS. This is even worse because it's not caused by luck but own choice. If you are in bad luck, anyone also cannot escape, no matter how healthy, fit and strong you are. If you are in good luck, even you smoke, drink and eat unhealthy also nothing will happen. True. Read a news about a centurion before. She smokes cigarettes for decades but still can live beyond 100. This morning over the radio, there is a Japanese man being the oldest man on earth. 112 years old. And he eats sweets every day. Diabetes don't want to find him. Luck, maybe. Link to post Share on other sites More sharing options...
DACH Supersonic April 11, 2018 Share April 11, 2018 Why you piak piak with HIV carrier ?And how you know the person has no HIV? Would they write that on their foreheads? Link to post Share on other sites More sharing options...
DACH Supersonic April 11, 2018 Share April 11, 2018 (edited) Why would you suspect your wife ? Mai lah. Take it easy.What if your wife says no to you one day? Women now demanding more respect and equality towards them. Think they will always give you? Then how you want to satisfy that urge? If you can kill that urge and mindset, then good for you. If not, then how? Find other people? And some women very bold these days hor. Can be trusted is subjective. Edited April 11, 2018 by DACH Link to post Share on other sites More sharing options...
RadX Moderator April 11, 2018 Share April 11, 2018 Ok here we go again Piak piak and leading to treasure life Same suspect as usual ↡ Advertisement 3 Link to post Share on other sites More sharing options...
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