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  1. Good news for the world. But pfizer and moderna are disappointing. mRNA supposed to be fast to develop, but now Apr, apparently still nothing, although they promised omicron-specific vaccine in Mar. Omicron-specific Sinopharm, Sinovac COVID vaccine candidates cleared for clinical trial BEIJING, April 16 (Reuters) - COVID-19 vaccine candidates developed by a Sinopharm subsidiary and Sinovac Biotech (SVA.O) to target the Omicron variant were approved for clinical trials in Hong Kong, the companies said on Saturday. Scientists worldwide are racing to study upgraded injections against Omicron, as data indicated that antibodies elicited by vaccines based on older strains show weaker activity to neutralise the highly transmissible variant. The two candidates from units of Sinopharm subsidiary China National Biotec Group (CNBG) and one from Sinovac contain inactivated or "killed" coronavirus and are similar to vaccines that the companies are supplying in China and overseas, the companies said in statements. The Sinopharm candidates will be tested as boosters in adults who have already received two or three vaccine doses, CNBG said. It did not specify which vaccine products the trial participants would have received before taking the experimental booster, or how many subjects would be recruited. Sinovac said it will push forward studies in its existing CoronaVac vaccine's protection against emerging variants. A Chinese study showed that a fourth dose of BBIBP-CorV, an existing Sinopharm COVID vaccine, did not significantly lift antibody levels against Omicron when administered six months after a third booster dose to a regular two-dose regimen. While the fourth dose restored antibody levels to around the peaks that followed the third dose, researchers said new vaccines would offer a better alternative as future boosters. Reporting by Roxanne Liu and Andrew Galbraith; Editing by Edmund Klamann and William Mallard
  2. Valneva says early studies show COVID-19 vaccine effective against Omicron Jan 19 (Reuters) - French biotech firm Valneva (VLS.PA) said on Wednesday that preliminary studies showed that three doses of its inactivated COVID-19 vaccine candidate neutralised the Omicron variant of the disease. All of the serum samples tested presented neutralizing antibodies against the ancestral virus and Delta variant, it said, while 87% of samples did so against the Omicron variant. "We are extremely pleased with these results," said Chief Medical Officer Juan Carlos Jaramillo in a statement, noting that these added to an earlier Phase III trial that showed improved immune response with two doses of the VLA2001 candidate. Valneva expects to receive potential approvals for its vaccine within the first three months of 2022, and is providing data to the European Medicines Agency (EMA) as well as regulators in the UK and Bahrain.
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